化工社化工社 化学情報印刷レポート · 研究参考用
Ethanol → 5-Bromo-2-[3,4-dihydro-1(2H)-quinolinyl]aniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | 1-(4-Bromo-2-nitrophenyl)-1,2,3,4-tetrahydroquinoline | HCID 13812927 | — |
| 触媒 | Platinum | HCID 23939 | — |
| 溶媒 | Benzene | HCID 241 | — |
| 生成物 | 5-Bromo-2-[3,4-dihydro-1(2H)-quinolinyl]aniline | HCID 13812931 | 100% |
反応手順
1-(4-Bromo-2-nitrophenyl)-1,2,3,4-tetrahydroquinoline (11.6 g, 0.035 mole) was dissolved in benzene (125 ml), and ethanol added (75 ml), followed by 1% platinum-on-charcoal (0.40 g). The mixture was shaken under an initial pressure of 56 psi for 6.5 hours. The mixture was filtered and the filtrate was evaporated at 50° C. under vacuum to provide 10.6 g (100%) of product, as a gum.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04723007 |
| 出典データセット | uspto-grants-1988_02 |
| ORD ID | ord-be31b5d785ad45829427ebbf59eaec37 |
| 出典メモ | uspto-grants-1988_02 |