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HRID 4044作成日:2026年10月23日

Ethanol → 5-Bromo-2-[3,4-dihydro-1(2H)-quinolinyl]aniline

https://huagongshe.com/ja/reaction/4044

反応式

関与物質

役割名称HCID仕込み量
反応物EthanolHCID 702—
反応物1-(4-Bromo-2-nitrophenyl)-1,2,3,4-tetrahydroquinolineHCID 13812927—
触媒PlatinumHCID 23939—
溶媒BenzeneHCID 241—
生成物5-Bromo-2-[3,4-dihydro-1(2H)-quinolinyl]anilineHCID 13812931100%

反応手順

1-(4-Bromo-2-nitrophenyl)-1,2,3,4-tetrahydroquinoline (11.6 g, 0.035 mole) was dissolved in benzene (125 ml), and ethanol added (75 ml), followed by 1% platinum-on-charcoal (0.40 g). The mixture was shaken under an initial pressure of 56 psi for 6.5 hours. The mixture was filtered and the filtrate was evaporated at 50° C. under vacuum to provide 10.6 g (100%) of product, as a gum.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US04723007
出典データセットuspto-grants-1988_02
ORD IDord-be31b5d785ad45829427ebbf59eaec37
出典メモuspto-grants-1988_02