関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 4-(Dimethylamino)Benzaldehyde | HCID 7479 | — |
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | 1-(5-Carboxy-pentyl)-2-methyl-pyridinium bromide | HCID 66643503 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | n-(5-Carboxypentyl)-4-(4-(dimethylamino)styryl)pyridinium bromide | HCID 66643380 | — |
反応手順
A mixture of 4-N,N-dimethylaminobenzaldehyde (3 g, 20 mmoles), N-(5-carboxy-pentyl)picolinium bromide (5.6 g, 20 mmoles) and piperidine (2 mL) in ethanol (100 mL) was heated at 60° C. overnight. The mixture was evaporated to dryness in vacuo. The residue was redissolved in methanol and then precipitated with ether to give the product (6.7 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08530195B2 |
|---|
| 出典データセット | uspto-grants-2013_09 |
|---|
| ORD ID | ord-af6963a81e4745939b0548827d31456a |
|---|
| 出典メモ | uspto-grants-2013_09 |
|---|
