N-(4-Bromo-benzyl)-N-(2,2-dimethoxy-ethyl)-4-methyl-benzenesulfonamide → N-(4-Bromo-3-chloro-benzyl)-N-(2,2-dimethoxy-ethyl)-4-methyl-benzene-sulfonamide

HRID 404721

反応式

HRID 404721 の反応式
[Br:1][C:2]1[CH:25]=[CH:24][C:5]([CH2:6][N:7]([CH2:18][CH:19]([O:22][CH3:23])[O:20][CH3:21])[S:8]([C:11]2[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1.BrC1C=CC(CNCC(OC)OC)=CC=1[Cl:41]>>[Br:1][C:2]1[CH:25]=[CH:24][C:5]([CH2:6][N:7]([CH2:18][CH:19]([O:20][CH3:21])[O:22][CH3:23])[S:8]([C:11]2[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=2)(=[O:10])=[O:9])=[CH:4][C:3]=1[Cl:41]

参加物

3

反応物 2

HCID 59226245N-(4-Bromo-benzyl)-N-(2,2-dimethoxy-ethyl)-4-methyl-benzenesulfonamideHCID 59226250(4-Bromo-3-chloro-benzyl)-(2,2-dimethoxy-ethyl)-amine

生成物 1

HCID 59226258N-(4-Bromo-3-chloro-benzyl)-N-(2,2-dimethoxy-ethyl)-4-methyl-benzene-sulfonamide

実験手順

The title compound was prepared by the protocol described for N-(4-Bromo-benzyl)-N-(2,2-dimethoxy-ethyl)-4-methyl-benzenesulfonamide (2), starting from (4-Bromo-3-chloro-benzyl)-(2,2-dimethoxy-ethyl)-amine (7). Rt=1.93 min (Method C). Detected mass: 430.3/432.3 (M−OMe−).

出典と根拠

ORDレコード
ord-39d996204ac04cbca8c59d7db820f4cf
出典データセット
uspto-grants-2014_06
特許番号
US08748614B2

関連ノート

読み込み中…