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Chloromethyl pivalate → 3-[4-(3,3-Dimethyl-2-oxo-5-trifluoromethyl-2,3-dihydroindol-1-ylmethoxy)phenyl]hex-4-ynoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Chloromethyl pivalate | HCID 87885 | — |
| 反応物 | Methyl 3-(4-hydroxyphenyl)hex-4-ynoate | HCID 57835749 | — |
| 反応物 | 3,3-Dimethyl-5-(trifluoromethyl)indolin-2-one | HCID 58031719 | — |
| 生成物 | 3-[4-(3,3-Dimethyl-2-oxo-5-trifluoromethyl-2,3-dihydroindol-1-ylmethoxy)phenyl]hex-4-ynoic acid | HCID 54766925 | — |
反応手順
Analogously to example 1, 3,3-dimethyl-5-trifluoromethyl-1,3-dihydroindol-2-one, chloromethyl pivalate and methyl 3-(4-hydroxyphenyl)hex-4-ynoate were used to obtain 3-[4-(3,3-dimethyl-2-oxo-5-trifluoromethyl-2,3-dihydroindol-1-ylmethoxy)phenyl]hex-4-ynoic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08530413B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-a7437a70bed24e358008440ab46f21fe |
| 出典メモ | uspto-grants-2013_09 |