Ammonium Hydroxide → HCID 86605522、化合物

HRID 404999ノート

反応式

HRID 404999 の反応式
[OH-].[NH4+:2].[N:3]([CH2:6][CH2:7][CH2:8][S:9](Cl)(=[O:11])=[O:10])=[N+:4]=[N-:5]>C(O)C>[N:3]([CH2:6][CH2:7][CH2:8][S:9]([NH2:2])(=[O:11])=[O:10])=[N+:4]=[N-:5]

参加物

4

反応物 2

HCID 14923Ammonium HydroxideHCID 538209503-Azidopropane-1-sulfonyl chloride

生成物 1

HCID 86605522HCID 86605522、化合物収率 86%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Ammonium hydroxide (28%) (10 mL) was added to a solution of 3-azido-1-propanesulfonyl chloride (˜2.29 g, 12.53 mmol; obtained in step 2) in ethanol (10 mL). The reaction mixture was stirred at room temperature for 3 h then concentrated. The residual material was passed through a short silica gel column using hexanes:ethyl acetate as eluent to isolate 3-azido-1-propanesulfonamide (1.5 g, 86%).

後処理

  1. concentrationthen concentrated

出典と根拠

ORDレコード
ord-44f2ef1886bf4c5a910a7febca11a14d
出典データセット
uspto-grants-2014_06
特許番号
US08748656B2

反応ノート

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