3-Bromobenzaldehyde → 4-(3-Bromo-benzyl)-piperazine-1-carboxylic acid phenylamide

HRID 40614

反応式

HRID 40614 の反応式
[C:1]1([NH:7][C:8]([N:10]2[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:16][C:17]1[CH:18]=[C:19]([CH:22]=[CH:23][CH:24]=1)[CH:20]=O>>[C:1]1([NH:7][C:8]([N:10]2[CH2:15][CH2:14][N:13]([CH2:20][C:19]3[CH:22]=[CH:23][CH:24]=[C:17]([Br:16])[CH:18]=3)[CH2:12][CH2:11]2)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

3

反応物 2

HCID 765833-BromobenzaldehydeHCID 7015289N-phenylpiperazine-1-carboxamide

生成物 1

HCID 171851254-(3-Bromo-benzyl)-piperazine-1-carboxylic acid phenylamide

実験手順

The title compound was prepared from piperazine-1-carboxylic acid phenylamide and 3-bromobenzaldehyde. 1H NMR (400 MHz, CDCl3): 7.50 (br s, 1H), 7.43-7.17 (m, 7H), 7.05-7.00 (m, 1H), 6.47 (br s, 1H), 3.52-3.45 (m, 6H), 2.48-2.42 (m, 4H).

出典と根拠

ORDレコード
ord-be19c54a6a7b4363ad6e79a44808b534
出典データセット
uspto-grants-2013_09
特許番号
US08530476B2

関連ノート

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