Ammonia → 2-Phthalimidoethanesulfonamide

HRID 40757

反応式

HRID 40757 の反応式
[C:1]1(=[O:17])[N:5]([CH2:6][CH2:7][S:8](Cl)(=[O:10])=[O:9])[C:4](=[O:12])[C:3]2=[CH:13][CH:14]=[CH:15][CH:16]=[C:2]12.[NH3:18]>O1CCOCC1.O>[C:1]1(=[O:17])[N:5]([CH2:6][CH2:7][S:8]([NH2:18])(=[O:10])=[O:9])[C:4](=[O:12])[C:3]2=[CH:13][CH:14]=[CH:15][CH:16]=[C:2]12

参加物

5

反応物 2

HCID 222AmmoniaHCID 3087392-Phthalimidoethanesulfonyl chloride

生成物 1

HCID 960922-Phthalimidoethanesulfonamide

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 312751,4-Dioxane溶媒

実験手順

2-Phthalimidoethanesulfonyl chloride (2.0 g) was added portion wise to a solution of 0.5 M of ammonia in dioxane (15 ml) and the solution obtained this way was stirred at room temperature. After 48 hours the reaction mixture was poured in water (50 ml) causing the title compound to precipitate. The product was collected by filtration. Yield: 1.52 g (83%) of a solid. 1H-NMR (DMSO-δ6) δ (ppm) 7.92-713 (m, 4H), 7.06 (s, 2H), 6.88-3.93 (m, 2H), 3.37-3.30 (m, 2H).

後処理

  1. customthe solution obtained this way

出典と根拠

ORDレコード
ord-01d3b421636a46c9afeff37871c6b667
出典データセット
uspto-grants-2013_09
特許番号
US08530486B2

関連ノート

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