反応式
[Cl:1][C:2]1[C:7]2[N:8]=C(N)[S:10][C:6]=2[CH:5]=[CH:4][CH:3]=1.[OH-].[K+].CC(O)=O>O>[NH2:8][C:7]1[C:2]([Cl:1])=[CH:3][CH:4]=[CH:5][C:6]=1[SH:10]参加物
5
反応条件
- 温度
- 150 °C
実験手順
The 4-chlorobenzo[d]thiazol-2-amine (2.00 g, 10.83 mmol) was combined with KOH (10.0 g, 178.2 mmol) and H2O (20 mL). The rsulting mixture was heated at 150° C. overnight. The solid became a thick paste overnight. After 24 h, the mixture was allowed to cool to room temperatureand diluted with H2O. A solution of AcOH was added to bring the pH down to 4 to 5.
後処理
- waitAfter 24 h
- temperatureto cool to room temperatureand
出典と根拠
- ORDレコード
- ord-2ad08017ae52484e95441de1104e06c1
- 出典データセット
- uspto-grants-2014_06
- 特許番号
- US08759336B2
関連ノート
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