化工社化工社 化学情報印刷レポート · 研究参考用
1-Naphthol → 1-Dichlorophosphoryloxynaphthalene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Naphthol | HCID 7005 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Phosphorus oxychloride | HCID 24813 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 1-Dichlorophosphoryloxynaphthalene | HCID 575631 | 90% |
反応手順
Phosphorus oxychloride (1.94 mL, 1 equiv) and α-naphthol (Aldrich, 3 g, 1 equiv) were stirred in anhydrous diethyl ether (20 mL). Anhydrous triethylamine was added (2.90 mL, 1 equiv) at −78° C. and the solution was allowed to warm to room temperature after 25 min. The triethylamine hydrochloride salt was filtered off and the solvent was removed under reduced pressure to give a clear pale yellow oil (4.88 g, 90%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08759318B2 |
| 出典データセット | uspto-grants-2014_06 |
| ORD ID | ord-60fb9df45ea44f87932f011862e456c1 |
| 出典メモ | uspto-grants-2014_06 |