Methanol → HCID 66895058、化合物

HRID 409613ノート

反応式

HRID 409613 の反応式
[CH3:1][CH:2]1[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]1C=O.[CH:13]1([NH2:23])[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15][CH2:14]1.[CH3:24]O>>[CH3:1][CH:2]1[CH2:10][C:9]2[C:4](=[C:5]([CH:24]=[N:23][CH:13]3[C:22]4[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=4)[CH2:16][CH2:15][CH2:14]3)[CH:6]=[CH:7][CH:8]=2)[NH:3]1

参加物

4

反応物 3

HCID 887MethanolHCID 180661,2,3,4-Tetrahydro-1-naphthylamineHCID 127981582-Methyl-2,3-dihydro-1H-indole-1-carbaldehyde

生成物 1

HCID 66895058HCID 66895058、化合物

実験手順

1.68 g of 2-methylindolino aldehyde was dissolved in 35 ml of methanol and then 1.58 ml of 1,2,3,4-tetrahydro naphthyl amine was slowly added thereto. The mixture was stirred at room temperature overnight before some precipitates were slowly formed, and then was filtered while being washed with methanol to provide ivory solids as a clean product (2.3 g). (Yield: 75%) This compound was a mixture of two stereoisomers at a ratio of 1:0.6.

後処理

  1. customwere slowly formed
  2. filtrationwas filtered
  3. washwhile being washed with methanol

出典と根拠

ORDレコード
ord-f6f7a432e2e34bf48f7216466847115b
出典データセット
uspto-grants-2014_06
特許番号
US08759461B2

反応ノート

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