化工社化工社 化学情報印刷レポート · 研究参考用
6-Fluoroindole → Sodium 6-Fluoro-1H-indole-2-sulfonate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 6-Fluoroindole | HCID 351278 | — |
| 反応物 | Sodium Bisulfite | HCID 23665763 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Sodium 6-Fluoro-1H-indole-2-sulfonate | HCID 86634332 | 29.5% |
反応手順
To a solution of 23.4 g sodium bisulfite in 80 ml water a solution of 13.5 g 6-fluoro indole in ethanol is added drop wise. The obtained suspension is stirred at room temperature over night. The precipitate is filtered and washed with cold water, cold methanol and diethyl ether. 7.0 g (29%) of the title compound are obtained as a colourless solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08530493B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-524347121123467c90bcf38b3fc5d8c2 |
| 出典メモ | uspto-grants-2013_09 |