Isobutylamine → Methyl 4-[(2-methylpropyl)amino]-3-nitrobenzoate
反応式
Cl[C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[CH2:15]([NH2:19])[CH:16]([CH3:18])[CH3:17]>CN(C=O)C>[CH3:9][O:8][C:6](=[O:7])[C:5]1[CH:10]=[CH:11][C:2]([NH:19][CH2:15][CH:16]([CH3:18])[CH3:17])=[C:3]([N+:12]([O-:14])=[O:13])[CH:4]=1参加物
4
実験手順
4-Isobutylamino-3-nitro-benzoic acid methyl ester (950.0 mg) was prepared by following General Procedure A starting from methyl 4-chloro-3-nitrobenzoate (1.0 g) and isobutyl amine (402.0 mg) in DMF (10.0 mL). The crude product was used in the next step without further purification.
後処理
- customThe crude product was used in the next step without further purification
出典と根拠
- ORDレコード
- ord-78d043cda1874fedb620d3037bde705b
- 出典データセット
- uspto-grants-2014_06
- 特許番号
- US08759535B2
反応ノート
読み込み中…