Methylamine → 1-(4-(Methylamino)-3-nitrophenyl)ethanone

HRID 410952ノート

反応式

HRID 410952 の反応式
C[CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8](F)=[C:7]([N+:12]([O-:14])=[O:13])[CH:6]=1)=[O:4].[CH3:15][NH2:16]>CN(C=O)C>[CH3:15][NH:16][C:8]1[CH:9]=[CH:10][C:5]([C:3](=[O:4])[CH3:2])=[CH:6][C:7]=1[N+:12]([O-:14])=[O:13]

参加物

4

反応物 2

HCID 6329MethylamineHCID 534295611-(4-Fluoro-3-nitrophenyl)propan-1-one

生成物 1

HCID 131756261-(4-(Methylamino)-3-nitrophenyl)ethanone

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

1-(4-Methylamino-3-nitro-phenyl)-ethanone (153 mg) was prepared by following General Procedure A starting from methyl 1-(4-fluoro-3-nitro-phenyl)-ethanone (183 mg) and methylamine (2 M in THF, 1.0 ml) in DMF (5 mL). The crude product was used in the next step without further purification.

後処理

  1. customThe crude product was used in the next step without further purification

出典と根拠

ORDレコード
ord-a17ca1bab8414d6b9c8a975d903ef7a1
出典データセット
uspto-grants-2014_06
特許番号
US08759535B2

反応ノート

読み込み中…