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N-(2-Chloroethyl)dibenzylamine → [2-(2-Dibenzylamino-ethoxy)-ethyl]dimethyl-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-(2-Chloroethyl)dibenzylamine | HCID 5820 | — |
| 反応物 | 2-(Dimethylamino)ethanol | HCID 7902 | — |
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 触媒 | Tetrabutylammonium Bromide | HCID 74236 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | [2-(2-Dibenzylamino-ethoxy)-ethyl]dimethyl-amine | HCID 67332185 | — |
反応手順
[2-(2-Dibenzylamino-ethoxy)-ethyl]-dimethyl-amine was prepared following General Procedure S starting from dibenzyl-(2-chloro-ethyl)-amine (640 mg), 2-dimethylamino-ethanol (325 mg), 50% (w/w) KOH solution (3 mL) and tetrabutylammonium bromide (95 mg) in dioxane (3 mL).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08759535B2 |
| 出典データセット | uspto-grants-2014_06 |
| ORD ID | ord-4ae372d5b90a419eb5e8acf22be3a170 |
| 出典メモ | uspto-grants-2014_06 |