HCID 86656940、化合物 → 2-(6-Chloro-benzothiazol-2-ylamino)-1-(2-methoxy-ethyl)-1H-benzoimidazole-5-carboxylic acid piperidin-4-ylamide dihydrochloride
反応式
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([NH:14][C:15]([C:17]2[CH:40]=[CH:39][C:20]3[N:21]([CH2:35][CH2:36][O:37][CH3:38])[C:22]([NH:24][C:25]4[S:26][C:27]5[CH:33]=[C:32]([Cl:34])[CH:31]=[CH:30][C:28]=5[N:29]=4)=[N:23][C:19]=3[CH:18]=2)=[O:16])[CH2:10][CH2:9]1)=O)(C)(C)C>Cl.O1CCOCC1>[ClH:34].[ClH:34].[NH:8]1[CH2:9][CH2:10][CH:11]([NH:14][C:15]([C:17]2[CH:40]=[CH:39][C:20]3[N:21]([CH2:35][CH2:36][O:37][CH3:38])[C:22]([NH:24][C:25]4[S:26][C:27]5[CH:33]=[C:32]([Cl:34])[CH:31]=[CH:30][C:28]=5[N:29]=4)=[N:23][C:19]=3[CH:18]=2)=[O:16])[CH2:12][CH2:13]1参加物
4
実験手順
2-(6-Chloro-benzothiazol-2-ylamino)-1-(2-methoxy-ethyl)-1H-benzoimidazole-5-carboxylic acid piperidin-4-ylamide dihydrochloride (150 mg) was prepared by following General Procedure L starting from 4-{[2-(6-chloro-benzothiazol-2-ylamino)-1-(2-methoxy-ethyl)-1H-benzoimidazole-5-carbonyl]-amino}-piperidine-1-carboxylic acid tert-butyl ester (160 mg) in 4M HCl in dioxane (2 mL).