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HRID 411051作成日:2026年10月27日

(4-Methylamino-3-nitro-benzoylamino)-acetic acid tert-butyl ester → (4-Methylamino-3-nitro-benzoylamino)-acetic acid

https://huagongshe.com/reaction/411051

反応式

関与物質

役割名称HCID仕込み量
反応物(4-Methylamino-3-nitro-benzoylamino)-acetic acid tert-butyl esterHCID 67332520—
溶媒DichloromethaneHCID 6344—
溶媒1,4-Dioxane hydrochlorideHCID 20443148—
生成物(4-Methylamino-3-nitro-benzoylamino)-acetic acidHCID 6733464781.4%

反応手順

(4-Methylamino-3-nitro-benzoylamino)-acetic acid (800 mg) was prepared starting from (4-methylamino-3-nitro-benzoylamino)-acetic acid tert-butyl ester (1.2 g) in 4 M HCl-dioxane (2 mL) and DCM (2 mL). The reaction was stirred at room temperature for 8 h. The solvent was evaporated to isolate pure compound without any further purification.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08759535B2
出典データセットuspto-grants-2014_06
ORD IDord-040cee8d28ca45deb8dd242cb4abb8bb
出典メモuspto-grants-2014_06