化工社化工社 化学情報印刷レポート · 研究参考用
Benzenepropanoyl chloride → N-(3-phenylpropionyl)-D,L-alanine Isobutyl Ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzenepropanoyl chloride | HCID 64801 | — |
| 反応物 | 2-Methylpropyl 2-aminopropanoate hydrochloride | HCID 86200109 | — |
| 生成物 | N-(3-phenylpropionyl)-D,L-alanine Isobutyl Ester | HCID 15480461 | — |
反応手順
Following General Procedure BA above and using 3-phenylpropionyl chloride (Aldrich) and D,L-alanine iso-butyl ester hydrochloride (from Example BB above), the title compound was prepared as a solid having a melting point of from 51-54° C. The reaction was monitored by tlc on silica gel and purification was by extraction with Et2O followed by washes with aqueous K2CO3 and aqueous HCl.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06559141B2 |
| 出典データセット | uspto-grants-2003_05 |
| ORD ID | ord-d67ff70c34c949448ea6b844b7392692 |
| 出典メモ | uspto-grants-2003_05 |