(3-Methoxyphenyl)acetic acid → 2-[(3-Methoxyphenyl)acetamido]butyric acid isobutyl ester

HRID 411469

反応式

HRID 411469 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:9][C:10]([OH:12])=O)[CH:6]=[CH:7][CH:8]=1.[NH2:13][CH:14]([CH2:22][CH3:23])[C:15]([O:17][CH2:18][CH:19]([CH3:21])[CH3:20])=[O:16]>>[CH2:18]([O:17][C:15](=[O:16])[CH:14]([NH:13][C:10](=[O:12])[CH2:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=1)[CH2:22][CH3:23])[CH:19]([CH3:20])[CH3:21]

参加物

3

反応物 2

HCID 15719(3-Methoxyphenyl)acetic acidHCID 13743360Isobutyl 2-aminobutyrate

生成物 1

HCID 538243972-[(3-Methoxyphenyl)acetamido]butyric acid isobutyl ester

実験手順

Following General Procedure BI above and using 3-methoxyphenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

後処理

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. filtrationwas by filtration

出典と根拠

ORDレコード
ord-c924a251e25f4956928feccea14a945d
出典データセット
uspto-grants-2003_05
特許番号
US06559141B2

関連ノート

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