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4-Bromo-3-phenyl-1H-pyrazol-5-amine → HCID 178517164、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Bromo-3-phenyl-1H-pyrazol-5-amine | HCID 594319 | — |
| 反応物 | HCID 178418806 | HCID 178418806 | — |
| 反応物 | HCID 178517101 | HCID 178517101 | — |
| 反応物 | HCID 178517165 | HCID 178517165 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | HCID 178517164 | HCID 178517164 | — |
反応手順
The named compound is prepared by substituting E & Z-3-[(hydroxy)-methylene]-5-chloro-1,3-dihydro-indol-2-one for E & Z-3-[(hydroxy)-methylene]-1,3-dihydro-indol-2-one and 4-bromo-5-phenyl-1H-pyrazol-3-ylamine for 3-aminopyrazole in the reaction of Example 1. Specifically, E & Z-3-[(hydroxy)-methylene]-5-chloro-1,3-dihydro-indol-2-one (0.1820 gms.) is reacted with 0.4511 gms. of 4-bromo-5-phenyl-1H-pyrazol-3-ylamine by refluxing in tetrahydrofuran (3.0 mL).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06559173B1 |
| 出典データセット | uspto-grants-2003_05 |
| ORD ID | ord-b0a8ba0eebec43e5920d546093ddbc02 |
| 出典メモ | uspto-grants-2003_05 |