Cesium carbonate → 8-(1-(3-fluorophenyl)pyrrolidin-2-yl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide

反応式

[CH3:1][N:2]([CH3:27])[C:3]([C:5]1[CH:6]=[C:7]2[C:12](=[C:13]([CH:15]3[CH2:19][CH2:18][CH2:17][NH:16]3)[CH:14]=1)[O:11][C:10]([N:20]1[CH2:25][CH2:24][O:23][CH2:22][CH2:21]1)=[CH:9][C:8]2=[O:26])=[O:4].Br[C:29]1[CH:34]=[CH:33][CH:32]=[C:31]([F:35])[CH:30]=1.CC1(C)C2C=CC=C(P(C3C=CC=CC=3)C3C=CC=CC=3)C=2OC2C1=CC=CC=2P(C1C=CC=CC=1)C1C=CC=CC=1.C(=O)([O-])[O-].[Cs+].[Cs+]>O1CCOCC1.C(O[Pd]OC(=O)C)(=O)C>[F:35][C:31]1[CH:30]=[C:29]([N:16]2[CH2:17][CH2:18][CH2:19][CH:15]2[C:13]2[CH:14]=[C:5]([C:3]([N:2]([CH3:27])[CH3:1])=[O:4])[CH:6]=[C:7]3[C:12]=2[O:11][C:10]([N:20]2[CH2:25][CH2:24][O:23][CH2:22][CH2:21]2)=[CH:9][C:8]3=[O:26])[CH:34]=[CH:33][CH:32]=1