化工社化工社 化学情報印刷レポート · 研究参考用
Phenol → Methyl-4-(trans-5-decenyloxy)-benzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phenol | HCID 996 | — |
| 反応物 | Methyl 4-(octadecyloxy)benzoate | HCID 4189536 | — |
| 反応物 | 5-Decen-1-ol, (5E)- | HCID 5283292 | — |
| 反応物 | Diethyl azodicarboxylate | HCID 5462977 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | Methyl-4-(trans-5-decenyloxy)-benzoate | HCID 18521058 | 72% |
反応手順
DEAD (256 mg, 1.47 mmol), phenol 34 (194 mg, 1.28 mmol), alcohol 26j (200 mg, 1.28 mmol), and TPP (386 mg, 1.47 mmol) in 13 ml anhydrous ether were reacted according to the procedure for compound 35a. The crude product was purified via flash chromatography over silica gel with gradual elutions from 95/5 to 90/10 (v/v, Hex/EtOAc). Evaporation of the solvent yielded 266 mg (72%) of colorless liquid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06569504B1 |
| 出典データセット | uspto-grants-2003_05 |
| ORD ID | ord-f88af62debeb4184a7fbf0620da384ed |
| 出典メモ | uspto-grants-2003_05 |