Methanol → Methyl L-ornithine monohydrochloride

HRID 413835ノート

反応式

HRID 413835 の反応式
[ClH:1].[NH2:2][C@H:3]([C:8]([OH:10])=[O:9])[CH2:4][CH2:5][CH2:6][NH2:7].[CH3:11]O>>[ClH:1].[CH3:11][O:9][C:8](=[O:10])[C@H:3]([CH2:4][CH2:5][CH2:6][NH2:7])[NH2:2]

参加物

3

反応物 2

HCID 887MethanolHCID 76654Ornithine hydrochloride

生成物 1

HCID 6453904Methyl L-ornithine monohydrochloride収率 97%

実験手順

Into a stirred suspension of L-(+)-ornithine hydrochloride (Aldrich) in methanol was bubbled anhydrous hydrochloric acid gas until the solution was saturated. The reaction mixture was capped with a rubber septum and stirring was continued overnight at room temperature. The solvent was then stripped under reduced pressure and the residue triturated with ether. The resulting solid was dried under reduced pressure to afford L-(+)-ornithine methyl ester hydrochloride as a white solid (97% yield).

後処理

  1. customwas bubbled anhydrous hydrochloric acid gas until the solution
  2. customThe reaction mixture was capped with a rubber septum
  3. customthe residue triturated with ether
  4. customThe resulting solid was dried under reduced pressure

出典と根拠

ORDレコード
ord-40da3da314cc40db89dc2ac0e98b8829
出典データセット
uspto-grants-2003_05
特許番号
US06569851B1

反応ノート

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