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2-Isocyanatothiophene → (N'-((2-(2-Thiophene-yl)ethyl)aminocarbonyl)-L-alaninyl)amino-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepin-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Isocyanatothiophene | HCID 2776375 | — |
| 反応物 | 3-(L-alaninyl)amino-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepin-2-one | HCID 23552762 | — |
| 生成物 | (N'-((2-(2-Thiophene-yl)ethyl)aminocarbonyl)-L-alaninyl)amino-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepin-2-one | HCID 86758990 | — |
反応手順
Following General Procedure (5-A1) using 2-thiophene-yl isocyanate and 3-[(L-alaninyl)]amino-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepin-2-one, as described in Example 8-B above, the title compound was prepared. The molecular weight as determined by mass spectrometry (FD) was: (M+H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06569851B1 |
| 出典データセット | uspto-grants-2003_05 |
| ORD ID | ord-27f66d695ede4faa98323d6d95b1e560 |
| 出典メモ | uspto-grants-2003_05 |