Hydrochloric Acid → (1H-indene-3-yl)methylamine hydrochloride
反応式
O[C:2]1([CH2:11][NH2:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1.[ClH:13]>C(O)C>[ClH:13].[CH2:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[C:2]([CH2:11][NH2:12])=[CH:3]1参加物
4
実験手順
Two and three-tenth g of 1-hydroxyindanylmethylamine is dissolved in 100 ml of ethanol saturated with HCl . Reaction mixture is refluxed overnight. It is cooled to room temperature and volatiles are evaporated under reduced pressure. The residue is stirred with 300 ml anhydrous ether. Precipitated solid is filtered and dried affording 2.2 g (85%) of the (1H-indene-3-yl)methylamine hydrochloride having a melting point of 245° C. decomp.
後処理
- customReaction mixture
- temperatureis refluxed overnight
- customvolatiles are evaporated under reduced pressure
- customPrecipitated solid
- filtrationis filtered
- customdried
出典と根拠
- ORDレコード
- ord-d92c469402694c57b0e870cd7160263c
- 出典データセット
- uspto-grants-1988_12
- 特許番号
- US04791103
反応ノート
読み込み中…