Tetrafluoroboric acid → 3-Bromo-2-chloro-4,5-difluorobenzenediazonium tetrafluoroborate
反応式
[Br:1][C:2]1[C:3]([Cl:11])=[C:4]([CH:6]=[C:7]([F:10])[C:8]=1[F:9])[NH2:5].[N:12]([O-])=O.[Na+].[F:16][B-:17]([F:20])([F:19])[F:18].[H+]>O>[F:16][B-:17]([F:20])([F:19])[F:18].[Br:1][C:2]1[C:3]([Cl:11])=[C:4]([N+:5]#[N:12])[CH:6]=[C:7]([F:10])[C:8]=1[F:9]参加物
5
実験手順
To a suspension of 3-bromo-2-chloro-4,5-difluoroaniline (30.1 g) in 42% fluoroboric acid (180 ml) with stirring vigorously was added sodium nitrite (12 g) in water (30 ml) at -9° to 1° C. for 40 minutes. After stirred for 1.5 hours, the resulting precipitate was collected by filtration and washed with 42% fluoroboric acid and then with ether to give the title compound (35.6 g) as light yellow needles, mp>300° C.
後処理
- stirringAfter stirred for 1.5 hours
- filtrationthe resulting precipitate was collected by filtration
- washwashed with 42% fluoroboric acid
出典と根拠
- ORDレコード
- ord-eaf733e906b94e909b4999f7983faed1
- 出典データセット
- uspto-grants-1988_12
- 特許番号
- US04791225
反応ノート
読み込み中…