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Sodium Iodide → HCID 21280636、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Iodide | HCID 5238 | — |
| 反応物 | N-Methylaniline | HCID 7515 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 2-(2-(2-Chloroethoxy)ethoxy)ethanol | HCID 78871 | — |
| 溶媒 | 1-Butanol | HCID 263 | — |
| 生成物 | HCID 21280636 | HCID 21280636 | — |
反応手順
A mixture of freshly distilled N-methylaniline (116 g, 1.1 mol), potassium carbonate (175 g, 1.25 mol), sodium iodide (4 g, 0.025 mol), 2-[2-(2-chloroethoxy)ethoxy]ethanol (168 g, 1 mol), and 900 mL of butanol was heated at reflux for 72 hours under nitrogen with vigorous stirring. After cooling and filtration the butanol was evaporated at reduced pressure to leave a tan oil. The oil was fractionally distilled in vacuo, yielding 150 g (63%) as a colorless oil, bp 190°-191° C. (0.13 mm).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04792208 |
| 出典データセット | uspto-grants-1988_12 |
| ORD ID | ord-d37f2b412cce47ea9333d02b28415777 |
| 出典メモ | uspto-grants-1988_12 |