Ethanol → 5-Methoxy-1-methyl-1H-pyrazole-4-carboxylic acid
反応式
[CH3:1][N:2]1[C:6]([O:7][CH3:8])=[C:5]([C:9]([O:11]CC)=[O:10])[CH:4]=[N:3]1.C(O)C.[OH-].[K+]>O>[CH3:1][N:2]1[C:6]([O:7][CH3:8])=[C:5]([C:9]([OH:11])=[O:10])[CH:4]=[N:3]1参加物
5
実験手順
Ethyl 1-methyl-5-methoxypyrazole-4-carboxylate (1.4 g) was stirred at room temperature for 2 hours together with 30 ml of ethanol, 10 ml of water and 2 g of potassium hydroxide. Ethanol was removed from the reaction solution under reduced pressure. From the aqueous layer, 1.29 g (yield 99%) of the desired 1-methyl-5-methoxypyrazole-4-carboxylic acid was obtained by acid precipitation.
後処理
- customEthanol was removed from the reaction solution under reduced pressure
出典と根拠
- ORDレコード
- ord-9e17d5a606c4429f92471d4c1dfad08e
- 出典データセット
- uspto-grants-1988_12
- 特許番号
- US04792565
反応ノート
読み込み中…