Hydrochloric Acid → 4-[([1,1'-Biphenyl]-4-yl)oxy]butan-1-amine--hydrogen chloride (1/1)
反応式
[ClH:1].[C:2]1([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:7]=[CH:6][C:5]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][NH2:13])=[CH:4][CH:3]=1.C(OCC)C>CO>[ClH:1].[C:2]1([C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:7]=[CH:6][C:5]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][NH2:13])=[CH:4][CH:3]=1参加物
5
実験手順
A twofold stoichiometric excess of 3% hydrochloric acid in methanol is added to a methanolic solution of 1.0 g. of 4-(4-biphenyloxy)-1-aminobutane. Diethyl ether is added until precipitation is complete. The product is filtered, washed with ether, air dried and recrystallized to give 4-(4-biphenyloxy)-1-aminobutane hydrochloride, m.p. 202°-205° C.
後処理
- filtrationThe product is filtered
- washwashed with ether, air
- customdried
- customrecrystallized
出典と根拠
- ORDレコード
- ord-a13de8ef933b41629c9f4289901c9ff5
- 出典データセット
- uspto-grants-1988_12
- 特許番号
- US04792570
反応ノート
読み込み中…