Diethyl (2-hydroxyethyl)phosphonate → Diethyl 2-[[5-(o-chloro-p-trifluoromethyl-phenoxy)-2-nitrophenoxy]acetoxy]-ethylphosphonate

HRID 414650ノート

反応式

HRID 414650 の反応式
[Cl:1][C:2]1[CH:22]=[C:21]([C:23]([F:26])([F:25])[F:24])[CH:20]=[CH:19][C:3]=1[O:4][C:5]1[CH:6]=[CH:7][C:8]([N+:16]([O-:18])=[O:17])=[C:9]([CH:15]=1)[O:10][CH2:11][C:12](Cl)=[O:13].[OH:27][CH2:28][CH2:29][P:30](=[O:37])([O:34][CH2:35][CH3:36])[O:31][CH2:32][CH3:33]>>[Cl:1][C:2]1[CH:22]=[C:21]([C:23]([F:26])([F:25])[F:24])[CH:20]=[CH:19][C:3]=1[O:4][C:5]1[CH:6]=[CH:7][C:8]([N+:16]([O-:18])=[O:17])=[C:9]([CH:15]=1)[O:10][CH2:11][C:12]([O:27][CH2:28][CH2:29][P:30](=[O:37])([O:31][CH2:32][CH3:33])[O:34][CH2:35][CH3:36])=[O:13]

参加物

3

反応物 2

HCID 312225Diethyl (2-hydroxyethyl)phosphonateHCID 212815435-(o-Chloro-p-trifluoromethyl-phenoxy)-2-nitrophenoxy-acetyl chloride

生成物 1

HCID 21281502Diethyl 2-[[5-(o-chloro-p-trifluoromethyl-phenoxy)-2-nitrophenoxy]acetoxy]-ethylphosphonate

実験手順

by using 5-(o-chloro-p-trifluoromethyl-phenoxy)-2-nitrophenoxy-acetyl chloride and diethyl 2-hydroxyethylphosphonate there is obtained diethyl 2-[[5-(o-chloro-p-trifluoromethyl-phenoxy)-2-nitrophenoxy]acetoxy]-ethylphosphonate, 1H-NMR (CDCl3, 400 MHz) 7.96 ppm (d, 1H), 7.80 ppm (d, 1H), 7.59 ppm (q, 1H), 7.21 ppm (d, 1H), 6.71 ppm (d, 1H), 6.52 ppm (q, 1H), 4.78 ppm (s, 2H), 4.45 ppm (m, 2H), 4.12 ppm (m, 4H), 2.17 ppm (m, 2H), 1.33 ppm (tt, 6H);

出典と根拠

ORDレコード
ord-d68d410ad66a4f1d89df103b9b2d45cc
出典データセット
uspto-grants-1988_12
特許番号
US04792616

反応ノート

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