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HRID 414676作成日:2026年10月26日

4-Methyl-6-nitro-7-hydroxy-1-indanone → 6-Amino-4-methyl-7-hydroxy-1-indanone

https://huagongshe.com/reaction/414676

反応式

関与物質

役割名称HCID仕込み量
反応物4-Methyl-6-nitro-7-hydroxy-1-indanoneHCID 13604142—
触媒HCID 178418390HCID 178418390—
溶媒DimethylformamideHCID 6228—
生成物6-Amino-4-methyl-7-hydroxy-1-indanoneHCID 1360414377.8%

反応手順

Into a solution of 26.0 g of 4-methyl-6-nitro-7-hydroxy-1-indanone in 50 ml of dimethylformamide was added 2.6 g of 10% palladium carbon, then the mixture was subjected to a catalytic hydrogenation under an atmospheric pressure at 0° C. to a room temperature. The catalyst was removed by filtration and the solvent was removed by evaporation to obtain 17.3 g of 6-amino-4-methyl-7-hydroxy-1-indanone.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US04792628
出典データセットuspto-grants-1988_12
ORD IDord-a44c2083e6a84f01b2f3cd0be27a7c8b
出典メモuspto-grants-1988_12