化工社化工社 化学情報印刷レポート · 研究参考用
4-Methyl-6-nitro-7-hydroxy-1-indanone → 6-Amino-4-methyl-7-hydroxy-1-indanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Methyl-6-nitro-7-hydroxy-1-indanone | HCID 13604142 | — |
| 触媒 | HCID 178418390 | HCID 178418390 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 6-Amino-4-methyl-7-hydroxy-1-indanone | HCID 13604143 | 77.8% |
反応手順
Into a solution of 26.0 g of 4-methyl-6-nitro-7-hydroxy-1-indanone in 50 ml of dimethylformamide was added 2.6 g of 10% palladium carbon, then the mixture was subjected to a catalytic hydrogenation under an atmospheric pressure at 0° C. to a room temperature. The catalyst was removed by filtration and the solvent was removed by evaporation to obtain 17.3 g of 6-amino-4-methyl-7-hydroxy-1-indanone.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04792628 |
| 出典データセット | uspto-grants-1988_12 |
| ORD ID | ord-a44c2083e6a84f01b2f3cd0be27a7c8b |
| 出典メモ | uspto-grants-1988_12 |