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Hydrogen Bromide → HCID 68820841、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrogen Bromide | HCID 260 | — |
| 反応物 | Dimethyl Sulfoxide | HCID 679 | — |
| 反応物 | methyl N-[3-(6,7-dimethoxy-2-methylaminoquinazolin-4-yl)phenyl]terephthalamic acid | HCID 66646296 | — |
| 溶媒 | Isopropanol | HCID 3776 | — |
| 生成物 | HCID 68820841 | HCID 68820841 | — |
反応手順
Dimethyl sulfoxide (1 mL) and hydrobromic acid (40 μL) were added to methyl N-[3-(6,7-dimethoxy-2-methylaminoquinazolin-4-yl)phenyl]terephthalamic acid (100.90 mg). 2-Propanol (5 mL) was added to the mixture while heating the mixture, and the mixture was cooled to room temperature to be solidified. The solid was collected by filtration to yield the titled compound (108.92 mg).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08530654B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-c3aa049b7aa9465693f6054ed6d6261f |
| 出典メモ | uspto-grants-2013_09 |