2,3-Dichloro-4-hydroxybenzaldehyde → 3-(2,3-Dichloro-4-hydroxyphenyl)-1-(4-(4-(trifluoromethyl)phenyl)thien-2-yl)prop-2-en-1-one

HRID 416043ノート

反応式

HRID 416043 の反応式
[F:1][C:2]([F:18])([F:17])[C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:10]=[C:11]([C:14](=[O:16])[CH3:15])[S:12][CH:13]=2)=[CH:5][CH:4]=1.[Cl:19][C:20]1[C:27]([Cl:28])=[C:26]([OH:29])[CH:25]=[CH:24][C:21]=1[CH:22]=O>>[Cl:19][C:20]1[C:27]([Cl:28])=[C:26]([OH:29])[CH:25]=[CH:24][C:21]=1[CH:22]=[CH:15][C:14]([C:11]1[S:12][CH:13]=[C:9]([C:6]2[CH:5]=[CH:4][C:3]([C:2]([F:17])([F:1])[F:18])=[CH:8][CH:7]=2)[CH:10]=1)=[O:16]

参加物

3

反応物 2

HCID 5283802,3-Dichloro-4-hydroxybenzaldehydeHCID 591803041-(4-(4-(Trifluoromethyl)phenyl)thien-2-yl)ethanone

生成物 1

HCID 666237293-(2,3-Dichloro-4-hydroxyphenyl)-1-(4-(4-(trifluoromethyl)phenyl)thien-2-yl)prop-2-en-1-one

実験手順

3-(2,3-Dichloro-4-hydroxyphenyl)-1-(4-(4-(trifluoromethyl)phenyl)thien-2-yl)prop-2-en-1-one is prepared from 1-(4-(4-(trifluoromethyl)phenyl)thien-2-yl)ethanone and 2,3-dichloro-4-hydroxybenzaldehyde according to general procedure B. The evaporation residue is purified by silica-gel chromatography.

後処理

  1. customThe evaporation residue is purified by silica-gel chromatography

出典と根拠

ORDレコード
ord-0a871d3b32314fe0a82d80f4d4a049c1
出典データセット
uspto-grants-2012_01
特許番号
US08088819B2

反応ノート

読み込み中…