Monoethyl malonate → HCID 178516622、化合物

関与物質

反応手順

The compound was synthesized starting from 1H-benzo[d]imidazol-5-amine (0.890 g, 6.69 mmol), 4-(4,4-difluoropiperidin-1-yl)benzaldehyde (1.5 g, 6.69 mmol), 2-(ethoxycarbonyl)acetic acid (0.883 g, 6.69 mmol), 1-isocyano-2-methylpropan-2-yl methyl carbonate (1.05 g, 6.69 mmol) and sodium tert.-butoxide (0.713 g, 6.35 mmol) according to method 3.

情報源と証拠