反応式
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([NH2:10])=[CH:9][C:4]=2[N:3]=[CH:2]1.[O:11]1[CH2:16][CH2:15][CH:14]([C:17]2[CH:24]=[CH:23][C:20]([CH:21]=O)=[CH:19][CH:18]=2)[CH2:13][CH2:12]1.[C:25](OC(C)(C)C)(=[O:30])[CH2:26][C:27]([O-])=[O:28].C(=O)(OC)OC(C)(C)C[N+]#[C-].CC(C)([O-])C.[Na+]>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([N:10]3[CH:21]([C:20]4[CH:23]=[CH:24][C:17]([CH:14]5[CH2:15][CH2:16][O:11][CH2:12][CH2:13]5)=[CH:18][CH:19]=4)[C:27](=[O:28])[CH2:26][C:25]3=[O:30])=[CH:9][C:4]=2[N:3]=[CH:2]1参加物
6
実験手順
The compound was synthesized starting from 1H-benzo[d]imidazol-5-amine (1.04 g, 7.89 mmol), 4-(tetrahydro-2H-pyran-4-yl)benzaldehyde (1.0 g, 5.26 mmol), mono-tert-butyl malonate (0.84 g, 5.26 mmol), 1-isocyano-2-methylpropan-2-yl methyl carbonate (0.83 g, 5.26 mmol) and sodium tert.-butoxide (0.829 g, 7.39 mmol) according to method 5.
後処理
- customThe compound was synthesized
出典と根拠
- ORDレコード
- ord-2e7227c23df247d9a6549863a438121f
- 出典データセット
- uspto-grants-2013_09
- 特許番号
- US08530670B2
関連ノート
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