関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| 反応物 | 4,5-Diaminopyrimidine | HCID 83703 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | 7H-Purin-8-ol | HCID 229771 | 567.7% |
反応手順
Pyrimidine-4,5-diamine (1.1 g, 10 mmol) and 1,1′-carbonyl diimidazole 1.78 g, 1.1 mmol) were added to dioxane (15 mL) and the reaction mixture was stirred at 90° C. for 48 hours. The mixture was cooled and the precipitate was recovered by filtration, rinsed with cold dioxane, and dried to give 850 mg (61%) of 7,9-dihydro-purin-8-one.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08093275B2 |
|---|
| 出典データセット | uspto-grants-2012_01 |
|---|
| ORD ID | ord-ac24549e369046279c3dddef4a063ea3 |
|---|
| 出典メモ | uspto-grants-2012_01 |
|---|
