2,5-Dimethyl-1H-indole → 1-(2,5-Dimethylindol-3-yl)isoquinoline

反応式

[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7]([CH3:11])=[CH:6][CH:5]=2.Cl[C:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:16]=[CH:15][N:14]=1>>[CH3:1][C:2]1[NH:3][C:4]2[C:9]([C:10]=1[C:13]1[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[CH:16]=[CH:15][N:14]=1)=[CH:8][C:7]([CH3:11])=[CH:6][CH:5]=2

参加物

反応物 2

HCID 709652,5-Dimethyl-1H-indole

HCID 140539Isoquinoline, 1-chloro-

生成物 1

HCID 666518181-(2,5-Dimethylindol-3-yl)isoquinoline

実験手順

The sub-title compound was prepared by the method of Example 10 part a, using 2,5-dimethyl indole and 1-chloroisoquinoline.

出典と根拠

ORDレコード: ord-1877c398521349bea7b6d2945dfc9859
出典データセット: uspto-grants-2012_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08093278B2

反応ノート

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