戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 418574作成日：2026年10月25日

N1-(3-fluoro-4-(thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-phenylmalonamide → N1-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-phenylmalonamide

https://huagongshe.com/reaction/418574

反応式

関与物質

役割名称HCID仕込み量
反応物N1-(3-fluoro-4-(thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-phenylmalonamideHCID 45488043—
反応物3-Fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)benzenamineHCID 59424507—
生成物N1-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-phenylmalonamideHCID 44565164—

反応手順

Following the procedure described for compound 5a (example 1, step 5) but substituting amine 9 for compound 12, title compound 5c was obtained as a white solid (78% yield). MS (m/z): 502.0 (M+H).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08093264B2
出典データセットuspto-grants-2012_01
ORD IDord-40a56a0c3f2c4a72ad2decfc47ae1db6
出典メモuspto-grants-2012_01