Ammonia → 5-Aminobenzene-1,3-diol
反応式
[OH:1][C:2]1[CH:7]=[C:6](O)[CH:5]=[C:4]([OH:9])[CH:3]=1.[NH3:10]>O>[OH:1][C:2]1[CH:7]=[C:6]([CH:5]=[C:4]([OH:9])[CH:3]=1)[NH2:10]参加物
4
実験手順
To a 200-mL, 2-necked flask was added 31.5 g (250 mmol) of 1,3,5-trihydroxybenzene. After replaced with argon, 25 mL of 28% ammonia and water were added thereto, and the resulting mixture was stirred in a water bath for 18 hours. Water was removed away in vacuo and 50 mL of isopropanol was added. The obtained mixture was ice-cooled for 2 hours to precipitate a solid and the precipitated solid was obtained by filtration. The solid was washed with isopropanol and then vacuum-dried, whereby a desired product was obtained (Quantity: 11.4 g, 91.3 mmol, Yield: 37%).
後処理
- additionwere added
- customWater was removed away in vacuo and 50 mL of isopropanol
- additionwas added
- temperaturecooled for 2 hours
- customto precipitate a solid
- customthe precipitated solid was obtained by filtration
- washThe solid was washed with isopropanol
- customvacuum-dried
出典と根拠
- ORDレコード
- ord-bf61faecc2664dc69570e273eab33397
- 出典データセット
- uspto-grants-2012_01
- 特許番号
- US08093349B2
反応ノート
読み込み中…