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3-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride) → 3-Methyl-5-nitro-2-(3-(trifluoromethoxy)phenyl)pyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride) | HCID 2734385 | — |
| 反応物 | 2-Bromo-3-methyl-5-nitropyridine | HCID 5200466 | — |
| 生成物 | 3-Methyl-5-nitro-2-(3-(trifluoromethoxy)phenyl)pyridine | HCID 67393780 | 91% |
反応手順
Obtained (1.25 g, yield 91%) following the procedure described in Intermediate 27, starting with 2-bromo-3-methyl-5-nitropyridine (4.61 mmol, 1.0 g), 3-(trifluoromethoxy)phenyl boronic acid (4.61 mmol, 0.95 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08536165B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-7da434c3faf646b18a54584636098cab |
| 出典メモ | uspto-grants-2013_09 |