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Benzoyl Peroxide → Methyl 2-(bromomethyl)-3-nitrobenzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzoyl Peroxide | HCID 7187 | — |
| 反応物 | Succinimide | HCID 11439 | — |
| 反応物 | N-bromobutanimide | HCID 67184 | — |
| 反応物 | Methyl 2-methyl-3-nitrobenzoate | HCID 601165 | — |
| 溶媒 | Carbon Tetrachloride | HCID 5943 | — |
| 生成物 | Methyl 2-(bromomethyl)-3-nitrobenzoate | HCID 1487795 | — |
反応手順
25.55 g (130.9 mmol) of 2-methyl-3-nitrobenzoic acid methyl ester is added to 300 ml of carbon tetrachloride, and mixed with 25.6 g (141.7 mmol) of N-bromosuccinimide and 62.8 mg of benzoyl peroxide. After seven days of refluxing, the succinimide is suctioned off after cooling, and then the filtrate is spun in until a dry state is reached. The desired compound that is incorporated in crude form into the next stage remains.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08097627B2 |
| 出典データセット | uspto-grants-2012_01 |
| ORD ID | ord-bac3f96a75ac43479751c769eee1363d |
| 出典メモ | uspto-grants-2012_01 |