Benzenamine, 3,5-bis(trifluoromethyl)- → N-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-5-pyrrol-1-yl-benzamide

HRID 421059

反応式

HRID 421059 の反応式
[OH:1][C:2]1[CH:10]=[CH:9][C:8]([N:11]2[CH:15]=[CH:14][CH:13]=[CH:12]2)=[CH:7][C:3]=1[C:4]([OH:6])=O.[F:16][C:17]([F:30])([F:29])[C:18]1[CH:19]=[C:20]([CH:22]=[C:23]([C:25]([F:28])([F:27])[F:26])[CH:24]=1)[NH2:21]>>[F:16][C:17]([F:29])([F:30])[C:18]1[CH:19]=[C:20]([NH:21][C:4](=[O:6])[C:3]2[CH:7]=[C:8]([N:11]3[CH:15]=[CH:14][CH:13]=[CH:12]3)[CH:9]=[CH:10][C:2]=2[OH:1])[CH:22]=[C:23]([C:25]([F:26])([F:28])[F:27])[CH:24]=1

参加物

3

反応物 2

HCID 9480Benzenamine, 3,5-bis(trifluoromethyl)-HCID 8537522-Hydroxy-5-(1H-pyrrol-1-yl)benzoic acid

生成物 1

HCID 10319590N-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-5-pyrrol-1-yl-benzamide収率 57.8%

実験手順

Using 2-hydroxy-5-(pyrrol-1-yl)benzoic acid and 3,5-bis(trifluoromethyl)-aniline as the raw materials, the same operation as the example 16 gave the title compound.

出典と根拠

ORDレコード
ord-b956a41ef6a840729d9e72e1809df8dd
出典データセット
uspto-grants-2012_01
特許番号
US08097759B2

関連ノート

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