5-Chlorosalicylic Acid → 5-Chloro-2-hydroxy-N [2-methyl-5-(trifluoromethyl)phenyl]benzamide

HRID 421106

反応式

HRID 421106 の反応式
[Cl:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[CH3:12][C:13]1[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:14]=1[NH2:15]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:15][C:14]1[CH:16]=[C:17]([C:20]([F:21])([F:22])[F:23])[CH:18]=[CH:19][C:13]=1[CH3:12])=[O:9]

参加物

3

反応物 2

HCID 94475-Chlorosalicylic AcidHCID 27359332-Methyl-5-(trifluoromethyl)aniline

生成物 1

HCID 178601255-Chloro-2-hydroxy-N [2-methyl-5-(trifluoromethyl)phenyl]benzamide収率 73.3%

実験手順

Using 5-chlorosalicylic acid and 2-methyl-5-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

出典と根拠

ORDレコード
ord-574bb38d69714985a2fd43f0347dfd8f
出典データセット
uspto-grants-2012_01
特許番号
US08097759B2

関連ノート

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