5-Methylsalicylic acid → 2-Hydroxy 5-methyl-N-[2-methyl-5-(trifluoromethyl)phenyl]benzamide

HRID 421119

反応式

HRID 421119 の反応式
[CH3:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[CH3:12][C:13]1[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:14]=1[NH2:15]>>[OH:11][C:5]1[CH:4]=[CH:3][C:2]([CH3:1])=[CH:10][C:6]=1[C:7]([NH:15][C:14]1[CH:16]=[C:17]([C:20]([F:21])([F:22])[F:23])[CH:18]=[CH:19][C:13]=1[CH3:12])=[O:9]

参加物

3

反応物 2

HCID 69735-Methylsalicylic acidHCID 27359332-Methyl-5-(trifluoromethyl)aniline

生成物 1

HCID 178601322-Hydroxy 5-methyl-N-[2-methyl-5-(trifluoromethyl)phenyl]benzamide収率 14.2%

実験手順

Using 5-methylsalicylic acid and 2-methyl-5-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

出典と根拠

ORDレコード
ord-59916b778efa495bb7de5397186a47c7
出典データセット
uspto-grants-2012_01
特許番号
US08097759B2

関連ノート

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