化工社化工社 化学情報印刷レポート · 研究参考用
Methylhydrazine → Ethyl 2-(methylhydrazono)propanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methylhydrazine | HCID 6061 | — |
| 反応物 | Ethyl pyruvate | HCID 12041 | — |
| 反応物 | Sulfuric acid magnesium salt (1:1) | HCID 24083 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | Ethyl 2-(methylhydrazono)propanoate | HCID 73828661 | 94% |
反応手順
To a suspension of ethyl pyruvate (37.8 mL, 338 mmol) and MgSO4 (40.8 g, 339 mmol) in CHCl3 (500 mL) was added a solution of methylhydrazine (18.0 mL, 332 mmol) in CHCl3 (100 mL) at 0° C. The reaction mixture was warmed to room temperature. After stirring for 24 hours at room temperature, the reaction mixture was filtered. The filtrate was concentrated under reduced pressure to give 44 g (94%) of the desired product that was used directly without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08101611B2 |
| 出典データセット | uspto-grants-2012_01 |
| ORD ID | ord-f1cbf88a550342928536cbe884acfa47 |
| 出典メモ | uspto-grants-2012_01 |