4,4,5,5-Tetramethyl-2-(2-methyl-4-(trifluoromethylsulfonyl)phenyl)-1,3,2-dioxaborolane → Methyl 4-methyl-3-(1-(2-methyl-4-(trifluoromethylsulfonyl)phenyl)phthalazin-6-yl)benzoate
反応式
CC1(C)C(C)(C)OB([C:9]2[CH:14]=[CH:13][C:12]([S:15]([C:18]([F:21])([F:20])[F:19])(=[O:17])=[O:16])=[CH:11][C:10]=2[CH3:22])O1.Cl[C:25]1[C:34]2[C:29](=[CH:30][C:31]([C:35]3[CH:36]=[C:37]([CH:42]=[CH:43][C:44]=3[CH3:45])[C:38]([O:40][CH3:41])=[O:39])=[CH:32][CH:33]=2)[CH:28]=[N:27][N:26]=1>>[CH3:45][C:44]1[CH:43]=[CH:42][C:37]([C:38]([O:40][CH3:41])=[O:39])=[CH:36][C:35]=1[C:31]1[CH:30]=[C:29]2[C:34](=[CH:33][CH:32]=1)[C:25]([C:9]1[CH:14]=[CH:13][C:12]([S:15]([C:18]([F:19])([F:20])[F:21])(=[O:16])=[O:17])=[CH:11][C:10]=1[CH3:22])=[N:26][N:27]=[CH:28]2参加物
3
実験手順
Methyl 4-methyl-3-(1-(2-methyl-4-(trifluoromethylsulfonyl)phenyl)phthalazin-6-yl)benzoate was prepared according to the procedure described in Example 223, using 4,4,5,5-tetramethyl-2-(2-methyl-4-(trifluoromethylsulfonyl)phenyl)-1,3,2-dioxaborolane and methyl 3-(1-chlorophthalazin-6-yl)-4-methylbenzoate as starting materials. MS (ESI, pos. ion) m/z: 500.9 (M+1).
出典と根拠
- ORDレコード
- ord-fbf78b296b63491d84d1138f5cca5b1b
- 出典データセット
- uspto-grants-2012_01
- 特許番号
- US08101612B2
反応ノート
読み込み中…