2-Fluoro-4-(methylsulfanyl)aniline → Methyl 2-(2-fluoro-4-(methylthio) phenylamino)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate

HRID 422825ノート

反応式

HRID 422825 の反応式
Cl[C:2]1[N:3]([CH3:13])[C:4](=[O:12])[CH:5]=[CH:6][C:7]=1[C:8]([O:10][CH3:11])=[O:9].[F:14][C:15]1[CH:20]=[C:19]([S:21][CH3:22])[CH:18]=[CH:17][C:16]=1[NH2:23]>>[F:14][C:15]1[CH:20]=[C:19]([S:21][CH3:22])[CH:18]=[CH:17][C:16]=1[NH:23][C:2]1[N:3]([CH3:13])[C:4](=[O:12])[CH:5]=[CH:6][C:7]=1[C:8]([O:10][CH3:11])=[O:9]

参加物

3

反応物 2

HCID 220256172-Fluoro-4-(methylsulfanyl)anilineHCID 57442171Methyl 2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate

生成物 1

HCID 66673753Methyl 2-(2-fluoro-4-(methylthio) phenylamino)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate

実験手順

Methyl 2-(2-fluoro-4-(methylthio)phenylamino)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate was prepared from methyl 2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate and 2-fluoro-4-(methylthio)benzenamine as described in Step C of Example 153.

出典と根拠

ORDレコード
ord-92bd32401d0148288a4a3e66740e44cb
出典データセット
uspto-grants-2012_01
特許番号
US08101639B2

反応ノート

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