化工社化工社 化学情報印刷レポート · 研究参考用
Ethanolamine → 2-Amino-4-beta-hydroxyethylamino-5-chloronitrobenzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanolamine | HCID 700 | — |
| 反応物 | 4,5-Dichloro-2-nitroaniline | HCID 81149 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | 2-Amino-4-beta-hydroxyethylamino-5-chloronitrobenzene | HCID 53727137 | — |
反応手順
0.11 mole (22.8 g) of 4,5-dichloro-2-nitroaniline is added to a solution of 0.55 mole (33.3 ml) of ethanolamine in 70 ml of dioxane. The reaction mixture is heated for 6 hours in refluxing dioxane. After dilution with water and neutralization with concentrated hydrochloric acid, the expected product precipitates.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04725283 |
| 出典データセット | uspto-grants-1988_02 |
| ORD ID | ord-b1ae56670021489c8b0a911be0cc61d1 |
| 出典メモ | uspto-grants-1988_02 |