関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1,2-Dichloroethane | HCID 11 | — |
| 反応物 | 6-Bromohexanoic acid | HCID 20210 | — |
| 反応物 | 2-Hydroxypropyl acrylate | HCID 61249 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 2-[(6-Bromohexanoyl)oxy]propyl acrylate | HCID 59005029 | — |
反応手順
To a 0° C. cooled mixture of 6-bromohexanoic acid (9.89 g), 2-hydroxypropyl acrylate (6 g), in CH2Cl2 (30 ml), EDC (7.89 g) was added. After being stirred for 30 min the reaction mixture was diluted with additional 20 ml of CH2Cl2 and stirring was continued for 16 h at room temperature. It was then filtered over celite and the filtrate was evaporated to dryness. The obtained beige-yellow residue was purified by silica column chromatography to give nearly pure material as transparent oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08105662B2 |
|---|
| 出典データセット | uspto-grants-2012_01 |
|---|
| ORD ID | ord-0e5407f232de4411a3a215497f6e7f7d |
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| 出典メモ | uspto-grants-2012_01 |
|---|
