2-Bromo-5-methylbenzoic acid → 2-Bromo-5-methyl-1-(methoxymethoxymethyl)benzene

反応式

[Br:1][C:2]1[CH:10]=[CH:9][C:8]([CH3:11])=[CH:7][C:3]=1[C:4](O)=[O:5].BrC1C=CC(Cl)=CC=1[CH2:20][O:21][CH2:22]OC>>[Br:1][C:2]1[CH:10]=[CH:9][C:8]([CH3:11])=[CH:7][C:3]=1[CH2:4][O:5][CH2:20][O:21][CH3:22]

参加物

反応物 2

HCID 2280802-Bromo-5-methylbenzoic acid

HCID 590246772-Bromo-5-chloro-1-(methoxymethoxymethyl)benzene

生成物 1

HCID 590087822-Bromo-5-methyl-1-(methoxymethoxymethyl)benzene

実験手順

This compound was made from 2-bromo-5-methylbenzoic acid in the same manner as compound 18d: 1H NMR (300 MHz, DMSO-d6) δ (ppm) 2.27 (s, 3H), 3.30 (s, 3H), 4.51 (s, 2H), 4.68 (s, 2H), 7.05 (dd, J=7.9, 2.3 Hz, 1H), 7.30 (d, J=1.5 Hz, 1H), 7.46 (d, J=8.2 Hz, 1H).

出典と根拠

ORDレコード: ord-684cad13069e4bb3983689576aff084b
出典データセット: uspto-grants-2012_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08106031B2

反応ノート

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