関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Methyl chloroformate | HCID 6586 | — |
| 反応物 | 2-(2-Methylthioethoxy)-phenylhydrazine | HCID 54289290 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 溶媒 | Diisopropylethylamine | HCID 81531 | — |
| 生成物 | 2-[2-(Methylthioethoxy)-phenyl]-hydrazinecarboxylic acid methyl ester | HCID 53833361 | — |
反応手順
5.6 ml of chloroformic acid methyl ester are added dropwise at 0° C. to 14.4 g of 2-(2-methylthioethoxy)-phenylhydrazine in 100 ml of tetrahydrofuran and 14 g of N-ethyldiisopropylamine. The reaction mixture is stirred at 20° C. for 2 hours; H2O is then added, and the mixture is repeatedly extracted with ethyl acetate. After customary further processing, a solid is obtained, and this is recrystallised from alcohol to thus yield the compond of the formula ##STR62## having a melting point of 92°-94° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US04725302 |
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| 出典データセット | uspto-grants-1988_02 |
|---|
| ORD ID | ord-e8648a916c7c4fcfb8175365162e18a3 |
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| 出典メモ | uspto-grants-1988_02 |
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